STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAP3K5Mitogen-activated protein kinase kinase kinase 5. (1366 aa)    
Predicted Functional Partners:
MAP2K6
Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily.
   
0.993
MAP2K3
Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily.
   
0.993
MAP2K4
Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily.
   
0.979
DAXX
Death domain associated protein.
    
 0.967
TRAF2
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.964
DAB2IP
DAB2 interacting protein.
    
 0.963
ERN1
Endoplasmic reticulum to nucleus signaling 1.
   
0.959
TXN
Thioredoxin; Belongs to the thioredoxin family.
    
 0.957
ENSFCAP00000054469
Thioredoxin domain-containing protein.
    
 0.957
PARK7
Parkinsonism associated deglycase.
    
 0.942
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.