STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC101097936Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (274 aa)    
Predicted Functional Partners:
KLK1
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
  
  
 
0.902
LOC101083957
ZnMc domain-containing protein.
   
 0.676
LAP3
Leucine aminopeptidase 3.
      
 0.601
TMSB10
Thymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family.
      
 0.578
LOC101090367
Uncharacterized protein; Belongs to the glycosyl hydrolase 22 family.
      
 0.577
ELANE
Elastase, neutrophil expressed; Belongs to the peptidase S1 family.
  
 
 0.562
MET
Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]
    
 0.560
CMA1
Chymase 1; Belongs to the peptidase S1 family.
  
 
  0.548
LOC101099923
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
  
 
  0.545
AR
Androgen receptor.
    
 0.543
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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