STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DOCK1Dedicator of cytokinesis 1; Belongs to the DOCK family. (1889 aa)    
Predicted Functional Partners:
ELMO2
Engulfment and cell motility 2.
    
 0.993
CRK
CRK proto-oncogene, adaptor protein.
    
 0.991
ELMO1
Engulfment and cell motility 1.
    
 0.986
ELMO3
Engulfment and cell motility 3.
    
 0.975
CRKL
CRK like proto-oncogene, adaptor protein.
    
 0.974
RAC2
Rac family small GTPase 2.
   
 0.963
RHOG
Ras homolog family member G.
   
 0.959
BCAR1
BCAR1 scaffold protein, Cas family member.
    
 0.947
PTK2
Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family.
   
 0.936
RAC3
Rac family small GTPase 3.
   
 0.651
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.