STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PYGBAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (843 aa)    
Predicted Functional Partners:
AGL
Amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase.
  
 0.996
GBE1
1,4-alpha-glucan-branching enzyme; Required for normal glycogen accumulation. The alpha 1-6 branches of glycogen play an important role in increasing the solubility of the molecule; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
 
 0.994
UGP2
UTP--glucose-1-phosphate uridylyltransferase.
   
 
 0.963
AMY2B
Alpha-amylase.
  
 0.957
PGM2
Phosphoglucomutase 2.
  
 
 0.956
PGM2L1
Phosphoglucomutase 2 like 1.
  
 
 0.956
PGM5
Phosphoglucomutase 5; Belongs to the phosphohexose mutase family.
  
 
 0.945
MGAM
Maltase-glucoamylase.
    
 0.933
ENSFCAP00000060733
P-type domain-containing protein; Belongs to the glycosyl hydrolase 31 family.
    
 0.933
RIPK3
Receptor interacting serine/threonine kinase 3.
   
 0.913
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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