RAB38 protein (Felis catus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

RAB38

RAB38, member RAS oncogene family. (211 aa)

Predicted Functional Partners:

HPS1

0.754

VAMP7

0.750

OCA2

0.742

RABGGTA

0.736

ANKRD27

0.726

CHM

0.686

SLC45A2

0.673

GAK

0.665

GDI2

0.646

HPS3

0.630

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANKRD27	GDI2	ENSFCAP00000002148	ENSFCAP00000011730	Ankyrin repeat domain 27.	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.	0.442
ANKRD27	RAB38	ENSFCAP00000002148	ENSFCAP00000007828	Ankyrin repeat domain 27.	RAB38, member RAS oncogene family.	0.726
ANKRD27	VAMP7	ENSFCAP00000002148	ENSFCAP00000022799	Ankyrin repeat domain 27.	Vesicle associated membrane protein 7; Belongs to the synaptobrevin family.	0.858
CHM	GDI2	ENSFCAP00000022942	ENSFCAP00000011730	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.	0.586
CHM	RAB38	ENSFCAP00000022942	ENSFCAP00000007828	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	RAB38, member RAS oncogene family.	0.686
CHM	RABGGTA	ENSFCAP00000022942	ENSFCAP00000005194	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	Rab geranylgeranyltransferase subunit alpha.	0.990
GAK	RAB38	ENSFCAP00000007628	ENSFCAP00000007828	Cyclin G associated kinase.	RAB38, member RAS oncogene family.	0.665
GAK	VAMP7	ENSFCAP00000007628	ENSFCAP00000022799	Cyclin G associated kinase.	Vesicle associated membrane protein 7; Belongs to the synaptobrevin family.	0.793
GDI2	ANKRD27	ENSFCAP00000011730	ENSFCAP00000002148	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.	Ankyrin repeat domain 27.	0.442
GDI2	CHM	ENSFCAP00000011730	ENSFCAP00000022942	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	0.586
GDI2	RAB38	ENSFCAP00000011730	ENSFCAP00000007828	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.	RAB38, member RAS oncogene family.	0.646
GDI2	RABGGTA	ENSFCAP00000011730	ENSFCAP00000005194	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.	Rab geranylgeranyltransferase subunit alpha.	0.712
HPS1	HPS3	ENSFCAP00000008670	ENSFCAP00000052490	HPS1 biogenesis of lysosomal organelles complex 3 subunit 1.	Hermansky-Pudlak syndrome 3 protein homolog; Involved in early stages of melanosome biogenesis and maturation.	0.720
HPS1	RAB38	ENSFCAP00000008670	ENSFCAP00000007828	HPS1 biogenesis of lysosomal organelles complex 3 subunit 1.	RAB38, member RAS oncogene family.	0.754
HPS3	HPS1	ENSFCAP00000052490	ENSFCAP00000008670	Hermansky-Pudlak syndrome 3 protein homolog; Involved in early stages of melanosome biogenesis and maturation.	HPS1 biogenesis of lysosomal organelles complex 3 subunit 1.	0.720
HPS3	RAB38	ENSFCAP00000052490	ENSFCAP00000007828	Hermansky-Pudlak syndrome 3 protein homolog; Involved in early stages of melanosome biogenesis and maturation.	RAB38, member RAS oncogene family.	0.630
HPS3	SLC45A2	ENSFCAP00000052490	ENSFCAP00000002173	Hermansky-Pudlak syndrome 3 protein homolog; Involved in early stages of melanosome biogenesis and maturation.	Solute carrier family 45 member 2.	0.423
HPS3	VAMP7	ENSFCAP00000052490	ENSFCAP00000022799	Hermansky-Pudlak syndrome 3 protein homolog; Involved in early stages of melanosome biogenesis and maturation.	Vesicle associated membrane protein 7; Belongs to the synaptobrevin family.	0.533
OCA2	RAB38	ENSFCAP00000000140	ENSFCAP00000007828	OCA2 melanosomal transmembrane protein.	RAB38, member RAS oncogene family.	0.742
OCA2	SLC45A2	ENSFCAP00000000140	ENSFCAP00000002173	OCA2 melanosomal transmembrane protein.	Solute carrier family 45 member 2.	0.760