NOD2 protein (Felis catus) - STRING interaction network

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Score

NOD2

Nucleotide binding oligomerization domain containing 2. (1014 aa)

Predicted Functional Partners:

RIPK2

0.997

ATG16L1

0.991

ERBIN

0.954

MAVS

0.952

AAMP

0.935

ATG5

0.920

ATG12

0.914

NOD1

0.862

TLR2

0.858

CASP4

0.770

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AAMP	NOD1	ENSFCAP00000002187	ENSFCAP00000038435	Angio associated migratory cell protein.	Nucleotide binding oligomerization domain containing 1.	0.592
AAMP	NOD2	ENSFCAP00000002187	ENSFCAP00000007886	Angio associated migratory cell protein.	Nucleotide binding oligomerization domain containing 2.	0.935
ATG12	ATG16L1	ENSFCAP00000007041	ENSFCAP00000010520	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Autophagy related 16 like 1.	0.999
ATG12	ATG5	ENSFCAP00000007041	ENSFCAP00000046882	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.999
ATG12	MAVS	ENSFCAP00000007041	ENSFCAP00000040337	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Mitochondrial antiviral signaling protein.	0.951
ATG12	NOD2	ENSFCAP00000007041	ENSFCAP00000007886	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Nucleotide binding oligomerization domain containing 2.	0.914
ATG16L1	ATG12	ENSFCAP00000010520	ENSFCAP00000007041	Autophagy related 16 like 1.	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	0.999
ATG16L1	ATG5	ENSFCAP00000010520	ENSFCAP00000046882	Autophagy related 16 like 1.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.999
ATG16L1	NOD1	ENSFCAP00000010520	ENSFCAP00000038435	Autophagy related 16 like 1.	Nucleotide binding oligomerization domain containing 1.	0.975
ATG16L1	NOD2	ENSFCAP00000010520	ENSFCAP00000007886	Autophagy related 16 like 1.	Nucleotide binding oligomerization domain containing 2.	0.991
ATG16L1	RIPK2	ENSFCAP00000010520	ENSFCAP00000016295	Autophagy related 16 like 1.	Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains.	0.428
ATG5	ATG12	ENSFCAP00000046882	ENSFCAP00000007041	Autophagy protein 5; Involved in autophagic vesicle formation.	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	0.999
ATG5	ATG16L1	ENSFCAP00000046882	ENSFCAP00000010520	Autophagy protein 5; Involved in autophagic vesicle formation.	Autophagy related 16 like 1.	0.999
ATG5	CASP4	ENSFCAP00000046882	ENSFCAP00000005500	Autophagy protein 5; Involved in autophagic vesicle formation.	Caspase-1 subunit p10; Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis. Upon inflammasome activation, during DNA virus infection but not RNA virus challenge, controls antiviral immunity through the cleavage of CGAS, rendering it inactive. In apoptotic cells, cleaves SPHK2 which is released from cells and remains enzymatically active extracell [...]	0.493
ATG5	MAVS	ENSFCAP00000046882	ENSFCAP00000040337	Autophagy protein 5; Involved in autophagic vesicle formation.	Mitochondrial antiviral signaling protein.	0.943
ATG5	NOD2	ENSFCAP00000046882	ENSFCAP00000007886	Autophagy protein 5; Involved in autophagic vesicle formation.	Nucleotide binding oligomerization domain containing 2.	0.920
CASP4	ATG5	ENSFCAP00000005500	ENSFCAP00000046882	Caspase-1 subunit p10; Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis. Upon inflammasome activation, during DNA virus infection but not RNA virus challenge, controls antiviral immunity through the cleavage of CGAS, rendering it inactive. In apoptotic cells, cleaves SPHK2 which is released from cells and remains enzymatically active extracell [...]	Autophagy protein 5; Involved in autophagic vesicle formation.	0.493
CASP4	NOD1	ENSFCAP00000005500	ENSFCAP00000038435	Caspase-1 subunit p10; Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis. Upon inflammasome activation, during DNA virus infection but not RNA virus challenge, controls antiviral immunity through the cleavage of CGAS, rendering it inactive. In apoptotic cells, cleaves SPHK2 which is released from cells and remains enzymatically active extracell [...]	Nucleotide binding oligomerization domain containing 1.	0.734
CASP4	NOD2	ENSFCAP00000005500	ENSFCAP00000007886	Caspase-1 subunit p10; Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis. Upon inflammasome activation, during DNA virus infection but not RNA virus challenge, controls antiviral immunity through the cleavage of CGAS, rendering it inactive. In apoptotic cells, cleaves SPHK2 which is released from cells and remains enzymatically active extracell [...]	Nucleotide binding oligomerization domain containing 2.	0.770
CASP4	TLR2	ENSFCAP00000005500	ENSFCAP00000020127	Caspase-1 subunit p10; Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis. Upon inflammasome activation, during DNA virus infection but not RNA virus challenge, controls antiviral immunity through the cleavage of CGAS, rendering it inactive. In apoptotic cells, cleaves SPHK2 which is released from cells and remains enzymatically active extracell [...]	Toll like receptor 2; Belongs to the Toll-like receptor family.	0.736