FCAR protein (Felis catus) - STRING interaction network

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Predicted Interactions

gene neighborhood

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Score

FCAR

Ig domain-containing protein. (176 aa)

Predicted Functional Partners:

KLRF2

0.843

MED21

0.730

MKNK2

0.717

AP3M1

0.706

NUP54

0.689

ARHGEF1

0.673

AP1S2

0.659

PLS1

0.651

UBE2D1

0.626

CLEC4E

0.620

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AP1S2	AP3M1	ENSFCAP00000047557	ENSFCAP00000000719	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	AP-3 complex subunit mu-1; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes; Belongs to the adaptor complexes medium subunit family.	0.663
AP1S2	ARHGEF1	ENSFCAP00000047557	ENSFCAP00000007530	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	Rho guanine nucleotide exchange factor 1.	0.537
AP1S2	FCAR	ENSFCAP00000047557	ENSFCAP00000007928	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	Ig domain-containing protein.	0.659
AP1S2	MED21	ENSFCAP00000047557	ENSFCAP00000036971	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.674
AP1S2	MKNK2	ENSFCAP00000047557	ENSFCAP00000011214	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	MAPK interacting serine/threonine kinase 2.	0.603
AP1S2	NUP54	ENSFCAP00000047557	ENSFCAP00000058134	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	Nucleoporin 54.	0.597
AP1S2	PLS1	ENSFCAP00000047557	ENSFCAP00000021858	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	Plastin 1.	0.668
AP1S2	UBE2D1	ENSFCAP00000047557	ENSFCAP00000053841	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family.	0.532
AP3M1	AP1S2	ENSFCAP00000000719	ENSFCAP00000047557	AP-3 complex subunit mu-1; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes; Belongs to the adaptor complexes medium subunit family.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.663
AP3M1	ARHGEF1	ENSFCAP00000000719	ENSFCAP00000007530	AP-3 complex subunit mu-1; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes; Belongs to the adaptor complexes medium subunit family.	Rho guanine nucleotide exchange factor 1.	0.626
AP3M1	FCAR	ENSFCAP00000000719	ENSFCAP00000007928	AP-3 complex subunit mu-1; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes; Belongs to the adaptor complexes medium subunit family.	Ig domain-containing protein.	0.706
AP3M1	MED21	ENSFCAP00000000719	ENSFCAP00000036971	AP-3 complex subunit mu-1; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes; Belongs to the adaptor complexes medium subunit family.	Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.712
AP3M1	MKNK2	ENSFCAP00000000719	ENSFCAP00000011214	AP-3 complex subunit mu-1; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes; Belongs to the adaptor complexes medium subunit family.	MAPK interacting serine/threonine kinase 2.	0.670
AP3M1	NUP54	ENSFCAP00000000719	ENSFCAP00000058134	AP-3 complex subunit mu-1; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes; Belongs to the adaptor complexes medium subunit family.	Nucleoporin 54.	0.662
AP3M1	PLS1	ENSFCAP00000000719	ENSFCAP00000021858	AP-3 complex subunit mu-1; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes; Belongs to the adaptor complexes medium subunit family.	Plastin 1.	0.667
AP3M1	UBE2D1	ENSFCAP00000000719	ENSFCAP00000053841	AP-3 complex subunit mu-1; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes; Belongs to the adaptor complexes medium subunit family.	Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family.	0.594
ARHGEF1	AP1S2	ENSFCAP00000007530	ENSFCAP00000047557	Rho guanine nucleotide exchange factor 1.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.537
ARHGEF1	AP3M1	ENSFCAP00000007530	ENSFCAP00000000719	Rho guanine nucleotide exchange factor 1.	AP-3 complex subunit mu-1; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes; Belongs to the adaptor complexes medium subunit family.	0.626
ARHGEF1	FCAR	ENSFCAP00000007530	ENSFCAP00000007928	Rho guanine nucleotide exchange factor 1.	Ig domain-containing protein.	0.673
ARHGEF1	MED21	ENSFCAP00000007530	ENSFCAP00000036971	Rho guanine nucleotide exchange factor 1.	Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.638