STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISY1Uncharacterized protein. (285 aa)    
Predicted Functional Partners:
CRNKL1
Crooked neck pre-mRNA splicing factor 1.
   
 0.997
PRPF19
Pre-mRNA processing factor 19.
    
 0.997
BUD31
BUD31 homolog.
   
 0.997
XAB2
XPA binding protein 2.
    
 0.997
RBM22
RNA binding motif protein 22.
   
 0.995
SNW1
SNW domain containing 1.
    
 0.993
AQR
RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.
 
  
 0.989
PRPF8
Pre-mRNA processing factor 8.
    
 0.981
SNRNP200
Small nuclear ribonucleoprotein U5 subunit 200.
    
 0.975
CDC5L
Cell division cycle 5 like.
    
 
 0.972
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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