STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PELI2E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (464 aa)    
Predicted Functional Partners:
IRAK1
Interleukin 1 receptor associated kinase 1.
    
 0.867
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.816
IRAK4
Interleukin 1 receptor associated kinase 4.
    
 0.776
IRAK2
Interleukin 1 receptor associated kinase 2.
    
 0.726
GPATCH4
G-patch domain containing 4.
      
 0.692
CADM2
Cell adhesion molecule 2.
      
 0.666
LOC101093034
Uncharacterized protein.
    
 0.653
TMEM189
Transmembrane protein 189.
    
 0.653
NOX3
NADPH oxidase 3.
      
 0.610
NUFIP2
Nuclear FMR1 interacting protein 2.
      
 0.610
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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