STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IWS1Interacts with SUPT6H, CTD assembly factor 1. (873 aa)    
Predicted Functional Partners:
SUPT6H
Transcription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family.
   
 0.997
TCEA1
Uncharacterized protein.
    
 0.957
CTDP1
RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.
   
 0.930
AFF4
AF4/FMR2 family member 4.
    
 0.926
SUPT5H
Transcription elongation factor SPT5.
   
 0.922
SUPT16H
SPT16 homolog, facilitates chromatin remodeling subunit.
   
 0.921
EAF2
ELL associated factor 2.
   
 
  0.921
EAF1
ELL associated factor 1.
   
 
  0.921
SSRP1
Tankyrase 1 binding protein 1.
   
 0.918
CHRNB1
DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the ligand-gated ion channel (TC 1.A.9) family.
   
 0.905
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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