STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SOCS6Suppressor of cytokine signaling 6. (497 aa)    
Predicted Functional Partners:
JAK2
Tyrosine-protein kinase.
    
 0.932
CUL5
Cullin-5; Belongs to the cullin family.
   
 0.784
CRADD
Uncharacterized protein.
     
0.770
STAT3
Signal transducer and activator of transcription.
   
 0.762
STAT5A
Signal transducer and activator of transcription.
   
 0.760
SOCS5
Suppressor of cytokine signaling 5.
     
0.751
STAT1
Signal transducer and activator of transcription.
   
 0.748
JAK1
Tyrosine-protein kinase.
    
 0.742
STAT5B
Signal transducer and activator of transcription.
   
 0.742
JAK3
Tyrosine-protein kinase.
    
 0.735
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.