STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PKHD1PKHD1 ciliary IPT domain containing fibrocystin/polyductin. (4078 aa)    
Predicted Functional Partners:
PKD1
Polycystin 1, transient receptor potential channel interacting.
      
 0.882
PKD2
Polycystin 2, transient receptor potential cation channel.
      
 0.850
NEK8
NIMA related kinase 8.
      
 0.820
ELF3
E74 like ETS transcription factor 3.
      
 0.624
ARL13B
ADP ribosylation factor like GTPase 13B.
      
 0.623
ANKS6
Ankyrin repeat and sterile alpha motif domain containing 6.
    
 0.577
IFT88
Intraflagellar transport 88.
     
 0.553
PMM2
Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions.
      
 0.552
AQP2
Aquaporin 2; Belongs to the MIP/aquaporin (TC 1.A.8) family.
   
  
 0.551
POC1A
POC1 centriolar protein A.
    
 
 0.548
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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