STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENKD1Enkurin domain containing 1. (346 aa)    
Predicted Functional Partners:
XRCC1
X-ray repair cross complementing 1.
   
 0.763
LOC105259694
Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family.
   
    0.672
ENSFCAP00000054410
Uncharacterized protein.
   
    0.672
LIG1
DNA ligase.
  
 0.654
TMEM129
Transmembrane protein 129.
   
  
 0.650
CLHC1
Clathrin heavy chain linker domain-containing protein 1.
      
 0.631
FEN1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
   
 0.623
GFOD2
Glucose-fructose oxidoreductase domain containing 2.
 
 
  
 0.600
LIG4
DNA ligase.
  
 0.595
LIG3
DNA ligase.
  
 0.554
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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