STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ICAM5Intercellular adhesion molecule 5. (923 aa)    
Predicted Functional Partners:
ITGAL
Integrin subunit alpha L; Belongs to the integrin alpha chain family.
    
 0.943
ACBD3
Acyl-CoA binding domain containing 3.
      
 0.751
OSBP
Oxysterol-binding protein; Belongs to the OSBP family.
      
 0.750
ITGB2
Integrin beta.
     
 0.687
C1QL4
Complement C1q like 4.
    
 0.651
NAXE
NAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
   
  
 0.630
ACBD4
Acyl-CoA binding domain containing 4.
      
 0.608
MXRA8
Matrix remodeling associated 8.
      
 0.549
NPEPL1
Aminopeptidase like 1.
    
 
 0.527
ITGAM
Integrin subunit alpha M; Belongs to the integrin alpha chain family.
    
 0.513
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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