STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TYK2Tyrosine-protein kinase. (1181 aa)    
Predicted Functional Partners:
IFNAR1
Interferon alpha and beta receptor subunit 1.
   
 0.999
SOCS1
Suppressor of cytokine signaling 1.
   
 0.998
STAT2
Signal transducer and activator of transcription.
   
 0.997
IL10RB
Interleukin 10 receptor subunit beta.
   
 0.996
IL12RB1
Interleukin 12 receptor subunit beta 1.
   
 0.996
JAK1
Tyrosine-protein kinase.
  
 
0.994
SOCS3
Suppressor of cytokine signaling 3.
   
 0.994
JAK2
Tyrosine-protein kinase.
  
0.994
STAT1
Signal transducer and activator of transcription.
   
 0.993
STAT3
Signal transducer and activator of transcription.
   
 0.991
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.