| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BTLA | CD40LG | ENSFCAP00000054222 | ENSFCAP00000033038 | B and T lymphocyte associated. | CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...] | 0.421 |
| BTLA | LTA | ENSFCAP00000054222 | ENSFCAP00000004152 | B and T lymphocyte associated. | Tumor necrosis factor ligand 1E; Belongs to the tumor necrosis factor family. | 0.415 |
| BTLA | TNFRSF14 | ENSFCAP00000054222 | ENSFCAP00000008830 | B and T lymphocyte associated. | TNF receptor superfamily member 14. | 0.705 |
| BTLA | TNFSF14 | ENSFCAP00000054222 | ENSFCAP00000026582 | B and T lymphocyte associated. | Tumor necrosis factor ligand 1D; Belongs to the tumor necrosis factor family. | 0.414 |
| CD40LG | BTLA | ENSFCAP00000033038 | ENSFCAP00000054222 | CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...] | B and T lymphocyte associated. | 0.421 |
| CD40LG | LTA | ENSFCAP00000033038 | ENSFCAP00000004152 | CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...] | Tumor necrosis factor ligand 1E; Belongs to the tumor necrosis factor family. | 0.688 |
| CD40LG | LTB | ENSFCAP00000033038 | ENSFCAP00000045551 | CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...] | Lymphotoxin beta; Belongs to the tumor necrosis factor family. | 0.535 |
| CD40LG | TNFRSF14 | ENSFCAP00000033038 | ENSFCAP00000008830 | CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...] | TNF receptor superfamily member 14. | 0.606 |
| CD40LG | TNFSF11 | ENSFCAP00000033038 | ENSFCAP00000005491 | CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...] | TNF superfamily member 11; Belongs to the tumor necrosis factor family. | 0.652 |
| CD40LG | TNFSF14 | ENSFCAP00000033038 | ENSFCAP00000026582 | CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...] | Tumor necrosis factor ligand 1D; Belongs to the tumor necrosis factor family. | 0.670 |
| CD40LG | TRAF2 | ENSFCAP00000033038 | ENSFCAP00000000359 | CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...] | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. | 0.624 |
| CD40LG | TRAF5 | ENSFCAP00000033038 | ENSFCAP00000028590 | CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...] | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. | 0.548 |
| LTA | BTLA | ENSFCAP00000004152 | ENSFCAP00000054222 | Tumor necrosis factor ligand 1E; Belongs to the tumor necrosis factor family. | B and T lymphocyte associated. | 0.415 |
| LTA | CD40LG | ENSFCAP00000004152 | ENSFCAP00000033038 | Tumor necrosis factor ligand 1E; Belongs to the tumor necrosis factor family. | CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...] | 0.688 |
| LTA | LTB | ENSFCAP00000004152 | ENSFCAP00000045551 | Tumor necrosis factor ligand 1E; Belongs to the tumor necrosis factor family. | Lymphotoxin beta; Belongs to the tumor necrosis factor family. | 0.998 |
| LTA | TNFRSF14 | ENSFCAP00000004152 | ENSFCAP00000008830 | Tumor necrosis factor ligand 1E; Belongs to the tumor necrosis factor family. | TNF receptor superfamily member 14. | 0.947 |
| LTA | TNFSF11 | ENSFCAP00000004152 | ENSFCAP00000005491 | Tumor necrosis factor ligand 1E; Belongs to the tumor necrosis factor family. | TNF superfamily member 11; Belongs to the tumor necrosis factor family. | 0.660 |
| LTA | TNFSF14 | ENSFCAP00000004152 | ENSFCAP00000026582 | Tumor necrosis factor ligand 1E; Belongs to the tumor necrosis factor family. | Tumor necrosis factor ligand 1D; Belongs to the tumor necrosis factor family. | 0.404 |
| LTA | TRAF2 | ENSFCAP00000004152 | ENSFCAP00000000359 | Tumor necrosis factor ligand 1E; Belongs to the tumor necrosis factor family. | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. | 0.466 |
| LTB | CD40LG | ENSFCAP00000045551 | ENSFCAP00000033038 | Lymphotoxin beta; Belongs to the tumor necrosis factor family. | CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...] | 0.535 |