STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SLC6A19Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (588 aa)    
Predicted Functional Partners:
CLTRN
Collectrin domain-containing protein.
   
 
 0.894
ACE2
Processed angiotensin-converting enzyme 2; Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator (By similarity). Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. By cleavage of angiotensin II, may be an important regulator of heart function (By similarity). By cleavage of angiotensin II, may also have a protective role in acute lung injury (By similarity). Plays an important role in amino acid transport by acting as binding partner of amino acid transporter SLC6A19 in [...]
   
 
 0.851
SLC1A5
Amino acid transporter.
  
  
 0.761
SLC1A3
Amino acid transporter.
  
  
 0.734
SLC1A1
Amino acid transporter.
  
  
 0.651
MS4A8
Membrane spanning 4-domains A8.
   
  
 0.637
DUPD1
Dual specificity phosphatase and pro isomerase domain containing 1; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.
      
 0.634
SLC38A3
Solute carrier family 38 member 3.
   
  
 0.614
SLC1A6
Amino acid transporter.
  
  
 0.596
SLC38A5
Solute carrier family 38 member 5.
   
  
 0.593
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.