FXR2 protein (Felis catus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

FXR2

FMR1 autosomal homolog 2. (673 aa)

Predicted Functional Partners:

FXR1

0.973

CYFIP2

0.966

CYFIP1

0.961

CPEB4

0.857

CPEB2

0.801

CPEB3

0.772

CPEB1

0.691

MPDU1

0.675

AGO2

0.648

FMR1

0.643

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGO2	CPEB1	ENSFCAP00000002557	ENSFCAP00000028781	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Uncharacterized protein.	0.417
AGO2	FMR1	ENSFCAP00000002557	ENSFCAP00000006702	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Fragile X mental retardation 1.	0.730
AGO2	FXR1	ENSFCAP00000002557	ENSFCAP00000060289	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	FMR1 autosomal homolog 1.	0.816
AGO2	FXR2	ENSFCAP00000002557	ENSFCAP00000008922	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	FMR1 autosomal homolog 2.	0.648
CPEB1	AGO2	ENSFCAP00000028781	ENSFCAP00000002557	Uncharacterized protein.	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	0.417
CPEB1	CPEB2	ENSFCAP00000028781	ENSFCAP00000022756	Uncharacterized protein.	Cytoplasmic polyadenylation element binding protein 2.	0.634
CPEB1	CPEB3	ENSFCAP00000028781	ENSFCAP00000028546	Uncharacterized protein.	Cytoplasmic polyadenylation element binding protein 3.	0.633
CPEB1	CPEB4	ENSFCAP00000028781	ENSFCAP00000034593	Uncharacterized protein.	Cytoplasmic polyadenylation element binding protein 4.	0.633
CPEB1	FMR1	ENSFCAP00000028781	ENSFCAP00000006702	Uncharacterized protein.	Fragile X mental retardation 1.	0.648
CPEB1	FXR1	ENSFCAP00000028781	ENSFCAP00000060289	Uncharacterized protein.	FMR1 autosomal homolog 1.	0.693
CPEB1	FXR2	ENSFCAP00000028781	ENSFCAP00000008922	Uncharacterized protein.	FMR1 autosomal homolog 2.	0.691
CPEB2	CPEB1	ENSFCAP00000022756	ENSFCAP00000028781	Cytoplasmic polyadenylation element binding protein 2.	Uncharacterized protein.	0.634
CPEB2	CPEB3	ENSFCAP00000022756	ENSFCAP00000028546	Cytoplasmic polyadenylation element binding protein 2.	Cytoplasmic polyadenylation element binding protein 3.	0.643
CPEB2	CPEB4	ENSFCAP00000022756	ENSFCAP00000034593	Cytoplasmic polyadenylation element binding protein 2.	Cytoplasmic polyadenylation element binding protein 4.	0.641
CPEB2	FMR1	ENSFCAP00000022756	ENSFCAP00000006702	Cytoplasmic polyadenylation element binding protein 2.	Fragile X mental retardation 1.	0.788
CPEB2	FXR1	ENSFCAP00000022756	ENSFCAP00000060289	Cytoplasmic polyadenylation element binding protein 2.	FMR1 autosomal homolog 1.	0.849
CPEB2	FXR2	ENSFCAP00000022756	ENSFCAP00000008922	Cytoplasmic polyadenylation element binding protein 2.	FMR1 autosomal homolog 2.	0.801
CPEB3	CPEB1	ENSFCAP00000028546	ENSFCAP00000028781	Cytoplasmic polyadenylation element binding protein 3.	Uncharacterized protein.	0.633
CPEB3	CPEB2	ENSFCAP00000028546	ENSFCAP00000022756	Cytoplasmic polyadenylation element binding protein 3.	Cytoplasmic polyadenylation element binding protein 2.	0.643
CPEB3	CPEB4	ENSFCAP00000028546	ENSFCAP00000034593	Cytoplasmic polyadenylation element binding protein 3.	Cytoplasmic polyadenylation element binding protein 4.	0.595