STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GDF15Growth differentiation factor 15. (307 aa)    
Predicted Functional Partners:
GFRAL
GDNF family receptor alpha like.
   
 
 0.848
RET
Ret proto-oncogene; Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
 
 0.759
TWSG1
Twisted gastrulation BMP signaling modulator 1.
   
 
 0.581
FSTL3
Follistatin like 3.
    
 0.532
TMEFF2
Transmembrane protein with EGF like and two follistatin like domains 2.
    
 0.523
CX3CL1
C-X3-C motif chemokine ligand 1.
    
 
 0.523
HAMP
Hepcidin antimicrobial peptide.
      
 0.497
FGF21
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
   
  
 0.496
ATF3
Activating transcription factor 3.
   
  
 0.492
RBM42
RNA binding motif protein 42.
      
 0.461
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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