STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAD2L1BPMAD2L1 binding protein. (274 aa)    
Predicted Functional Partners:
MAD2L1
Mitotic arrest deficient 2 like 1.
   
 
 0.940
TRIP13
Thyroid hormone receptor interactor 13; Belongs to the AAA ATPase family.
   
 
 0.917
CDC20
Cell division cycle 20.
   
 
 0.715
CDC20B
Cell division cycle 20B.
   
 
 0.715
DRAXIN
Draxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway.
      
 0.701
INPP5K
Inositol polyphosphate-5-phosphatase K.
    
 
 0.645
NUF2
NUF2 component of NDC80 kinetochore complex.
   
  
 0.625
CHST15
Carbohydrate sulfotransferase 15.
   
  
 0.624
AKAP12
A-kinase anchoring protein 12.
   
  
 0.616
FZR1
Fizzy and cell division cycle 20 related 1.
   
 
 0.567
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.