STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ITKTyrosine-protein kinase. (620 aa)    
Predicted Functional Partners:
LCP2
Lymphocyte cytosolic protein 2.
   
 0.988
VAV1
Vav guanine nucleotide exchange factor 1.
   
 0.982
PLCG1
Phosphoinositide phospholipase C.
   
0.975
VAV2
Vav guanine nucleotide exchange factor 2.
   
 0.961
TXK
Tyrosine-protein kinase.
  
 
 
0.960
VAV3
Vav guanine nucleotide exchange factor 3.
   
 0.960
HCK
Tyrosine-protein kinase.
  
0.958
TEC
Tyrosine-protein kinase.
  
  
 
0.950
LYN
Tyrosine-protein kinase.
  
0.942
SRC
Tyrosine-protein kinase.
  
0.931
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.