STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SERPINA5Serpin family A member 5; Belongs to the serpin family. (449 aa)    
Predicted Functional Partners:
PLAU
Plasminogen activator, urokinase.
    
 0.932
SERPINC1
Serpin family C member 1; Belongs to the serpin family.
  
0.927
PLAT
Plasminogen activator; Belongs to the peptidase S1 family.
    
 0.913
SERPINE1
Serpin family E member 1; Belongs to the serpin family.
  
  
0.828
SERPIND1
Serpin family D member 1; Belongs to the serpin family.
  
 
0.768
SERPINE2
Serpin family E member 2; Belongs to the serpin family.
  
  
0.752
SERPINB2
Serpin family B member 2; Belongs to the serpin family.
  
0.751
PROC
Vitamin K-dependent protein C; Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids. Exerts a protective effect on the endothelial cell barrier function. Belongs to the peptidase S1 family.
   
 0.643
F2
Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.
   
 0.604
SERPING1
Serpin family G member 1; Belongs to the serpin family.
  
0.602
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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