STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SERPINA3Serpin family A member 3; Belongs to the serpin family. (452 aa)    
Predicted Functional Partners:
SERPINC1
Serpin family C member 1; Belongs to the serpin family.
  
0.669
PLAU
Plasminogen activator, urokinase.
    
 0.634
SERPINB2
Serpin family B member 2; Belongs to the serpin family.
  
0.626
SERPIND1
Serpin family D member 1; Belongs to the serpin family.
  
 
 
0.622
PROC
Vitamin K-dependent protein C; Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids. Exerts a protective effect on the endothelial cell barrier function. Belongs to the peptidase S1 family.
   
 0.606
SERPING1
Serpin family G member 1; Belongs to the serpin family.
  
0.603
F2
Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.
   
 0.601
SERPINE2
Serpin family E member 2; Belongs to the serpin family.
  
  
 
0.598
FGG
Fibrinogen gamma chain.
   
 0.585
PLAT
Plasminogen activator; Belongs to the peptidase S1 family.
    
 0.582
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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