STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FBXO15F-box protein 15. (493 aa)    
Predicted Functional Partners:
ENSFCAP00000055272
Uncharacterized protein; Belongs to the SKP1 family.
    
 0.888
SKP1
Uncharacterized protein; Belongs to the SKP1 family.
    
 0.888
ISOC2
Isochorismatase domain containing 2.
      
 0.751
TAFA1
TAFA chemokine like family member 1.
      
 0.721
KALRN
Kalirin RhoGEF kinase.
    
 
 0.615
TIMM21
Translocase of inner mitochondrial membrane 21.
      
 0.607
EPN1
Epsin 1.
      
 0.592
NEDD8
NEDD8 ubiquitin like modifier.
    
 0.576
NAE1
NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.
    
 0.575
CUL1
Cullin 1; Belongs to the cullin family.
   
 0.568
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.