MAX protein (Felis catus) - STRING interaction network

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MAX

Protein max; Transcription regulator. Forms a sequence-specific DNA- binding protein complex with MYC or MAD which recognizes the core sequence 5'-CAC[GA]TG-3'. The MYC:MAX complex is a transcriptional activator, whereas the MAD:MAX complex is a repressor. May repress transcription via the recruitment of a chromatin remodeling complex containing H3 'Lys-9' histone methyltransferase activity (By similarity). Represses MYC transcriptional activity from E-box elements (By similarity). (411 aa)

Predicted Functional Partners:

MYC

0.997

MGA

0.990

MXD1

0.955

MAPK11

0.917

MAPK14

0.917

MAPK12

0.913

MXI1

0.911

ZBTB17

0.911

MYCN

0.895

MNT

0.869

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MAPK11	MAPK12	ENSFCAP00000011051	ENSFCAP00000031260	Mitogen-activated protein kinase.	Mitogen-activated protein kinase.	0.958
MAPK11	MAPK14	ENSFCAP00000011051	ENSFCAP00000023771	Mitogen-activated protein kinase.	Mitogen-activated protein kinase.	0.912
MAPK11	MAX	ENSFCAP00000011051	ENSFCAP00000044575	Mitogen-activated protein kinase.	Protein max; Transcription regulator. Forms a sequence-specific DNA- binding protein complex with MYC or MAD which recognizes the core sequence 5'-CAC[GA]TG-3'. The MYC:MAX complex is a transcriptional activator, whereas the MAD:MAX complex is a repressor. May repress transcription via the recruitment of a chromatin remodeling complex containing H3 'Lys-9' histone methyltransferase activity (By similarity). Represses MYC transcriptional activity from E-box elements (By similarity).	0.917
MAPK12	MAPK11	ENSFCAP00000031260	ENSFCAP00000011051	Mitogen-activated protein kinase.	Mitogen-activated protein kinase.	0.958
MAPK12	MAPK14	ENSFCAP00000031260	ENSFCAP00000023771	Mitogen-activated protein kinase.	Mitogen-activated protein kinase.	0.958
MAPK12	MAX	ENSFCAP00000031260	ENSFCAP00000044575	Mitogen-activated protein kinase.	Protein max; Transcription regulator. Forms a sequence-specific DNA- binding protein complex with MYC or MAD which recognizes the core sequence 5'-CAC[GA]TG-3'. The MYC:MAX complex is a transcriptional activator, whereas the MAD:MAX complex is a repressor. May repress transcription via the recruitment of a chromatin remodeling complex containing H3 'Lys-9' histone methyltransferase activity (By similarity). Represses MYC transcriptional activity from E-box elements (By similarity).	0.913
MAPK14	MAPK11	ENSFCAP00000023771	ENSFCAP00000011051	Mitogen-activated protein kinase.	Mitogen-activated protein kinase.	0.912
MAPK14	MAPK12	ENSFCAP00000023771	ENSFCAP00000031260	Mitogen-activated protein kinase.	Mitogen-activated protein kinase.	0.958
MAPK14	MAX	ENSFCAP00000023771	ENSFCAP00000044575	Mitogen-activated protein kinase.	Protein max; Transcription regulator. Forms a sequence-specific DNA- binding protein complex with MYC or MAD which recognizes the core sequence 5'-CAC[GA]TG-3'. The MYC:MAX complex is a transcriptional activator, whereas the MAD:MAX complex is a repressor. May repress transcription via the recruitment of a chromatin remodeling complex containing H3 'Lys-9' histone methyltransferase activity (By similarity). Represses MYC transcriptional activity from E-box elements (By similarity).	0.917
MAX	MAPK11	ENSFCAP00000044575	ENSFCAP00000011051	Protein max; Transcription regulator. Forms a sequence-specific DNA- binding protein complex with MYC or MAD which recognizes the core sequence 5'-CAC[GA]TG-3'. The MYC:MAX complex is a transcriptional activator, whereas the MAD:MAX complex is a repressor. May repress transcription via the recruitment of a chromatin remodeling complex containing H3 'Lys-9' histone methyltransferase activity (By similarity). Represses MYC transcriptional activity from E-box elements (By similarity).	Mitogen-activated protein kinase.	0.917
MAX	MAPK12	ENSFCAP00000044575	ENSFCAP00000031260	Protein max; Transcription regulator. Forms a sequence-specific DNA- binding protein complex with MYC or MAD which recognizes the core sequence 5'-CAC[GA]TG-3'. The MYC:MAX complex is a transcriptional activator, whereas the MAD:MAX complex is a repressor. May repress transcription via the recruitment of a chromatin remodeling complex containing H3 'Lys-9' histone methyltransferase activity (By similarity). Represses MYC transcriptional activity from E-box elements (By similarity).	Mitogen-activated protein kinase.	0.913
MAX	MAPK14	ENSFCAP00000044575	ENSFCAP00000023771	Protein max; Transcription regulator. Forms a sequence-specific DNA- binding protein complex with MYC or MAD which recognizes the core sequence 5'-CAC[GA]TG-3'. The MYC:MAX complex is a transcriptional activator, whereas the MAD:MAX complex is a repressor. May repress transcription via the recruitment of a chromatin remodeling complex containing H3 'Lys-9' histone methyltransferase activity (By similarity). Represses MYC transcriptional activity from E-box elements (By similarity).	Mitogen-activated protein kinase.	0.917
MAX	MGA	ENSFCAP00000044575	ENSFCAP00000038360	Protein max; Transcription regulator. Forms a sequence-specific DNA- binding protein complex with MYC or MAD which recognizes the core sequence 5'-CAC[GA]TG-3'. The MYC:MAX complex is a transcriptional activator, whereas the MAD:MAX complex is a repressor. May repress transcription via the recruitment of a chromatin remodeling complex containing H3 'Lys-9' histone methyltransferase activity (By similarity). Represses MYC transcriptional activity from E-box elements (By similarity).	MAX dimerization protein MGA.	0.990
MAX	MNT	ENSFCAP00000044575	ENSFCAP00000028347	Protein max; Transcription regulator. Forms a sequence-specific DNA- binding protein complex with MYC or MAD which recognizes the core sequence 5'-CAC[GA]TG-3'. The MYC:MAX complex is a transcriptional activator, whereas the MAD:MAX complex is a repressor. May repress transcription via the recruitment of a chromatin remodeling complex containing H3 'Lys-9' histone methyltransferase activity (By similarity). Represses MYC transcriptional activity from E-box elements (By similarity).	MAX network transcriptional repressor.	0.869
MAX	MXD1	ENSFCAP00000044575	ENSFCAP00000035907	Protein max; Transcription regulator. Forms a sequence-specific DNA- binding protein complex with MYC or MAD which recognizes the core sequence 5'-CAC[GA]TG-3'. The MYC:MAX complex is a transcriptional activator, whereas the MAD:MAX complex is a repressor. May repress transcription via the recruitment of a chromatin remodeling complex containing H3 'Lys-9' histone methyltransferase activity (By similarity). Represses MYC transcriptional activity from E-box elements (By similarity).	MAX dimerization protein 1.	0.955
MAX	MXI1	ENSFCAP00000044575	ENSFCAP00000004511	Protein max; Transcription regulator. Forms a sequence-specific DNA- binding protein complex with MYC or MAD which recognizes the core sequence 5'-CAC[GA]TG-3'. The MYC:MAX complex is a transcriptional activator, whereas the MAD:MAX complex is a repressor. May repress transcription via the recruitment of a chromatin remodeling complex containing H3 'Lys-9' histone methyltransferase activity (By similarity). Represses MYC transcriptional activity from E-box elements (By similarity).	MAX interactor 1, dimerization protein.	0.911
MAX	MYC	ENSFCAP00000044575	ENSFCAP00000045629	Protein max; Transcription regulator. Forms a sequence-specific DNA- binding protein complex with MYC or MAD which recognizes the core sequence 5'-CAC[GA]TG-3'. The MYC:MAX complex is a transcriptional activator, whereas the MAD:MAX complex is a repressor. May repress transcription via the recruitment of a chromatin remodeling complex containing H3 'Lys-9' histone methyltransferase activity (By similarity). Represses MYC transcriptional activity from E-box elements (By similarity).	Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity).	0.997
MAX	MYCN	ENSFCAP00000044575	ENSFCAP00000051060	Protein max; Transcription regulator. Forms a sequence-specific DNA- binding protein complex with MYC or MAD which recognizes the core sequence 5'-CAC[GA]TG-3'. The MYC:MAX complex is a transcriptional activator, whereas the MAD:MAX complex is a repressor. May repress transcription via the recruitment of a chromatin remodeling complex containing H3 'Lys-9' histone methyltransferase activity (By similarity). Represses MYC transcriptional activity from E-box elements (By similarity).	MYCN proto-oncogene, bHLH transcription factor.	0.895
MAX	ZBTB17	ENSFCAP00000044575	ENSFCAP00000057305	Protein max; Transcription regulator. Forms a sequence-specific DNA- binding protein complex with MYC or MAD which recognizes the core sequence 5'-CAC[GA]TG-3'. The MYC:MAX complex is a transcriptional activator, whereas the MAD:MAX complex is a repressor. May repress transcription via the recruitment of a chromatin remodeling complex containing H3 'Lys-9' histone methyltransferase activity (By similarity). Represses MYC transcriptional activity from E-box elements (By similarity).	Zinc finger and BTB domain containing 17.	0.911
MGA	MAX	ENSFCAP00000038360	ENSFCAP00000044575	MAX dimerization protein MGA.	Protein max; Transcription regulator. Forms a sequence-specific DNA- binding protein complex with MYC or MAD which recognizes the core sequence 5'-CAC[GA]TG-3'. The MYC:MAX complex is a transcriptional activator, whereas the MAD:MAX complex is a repressor. May repress transcription via the recruitment of a chromatin remodeling complex containing H3 'Lys-9' histone methyltransferase activity (By similarity). Represses MYC transcriptional activity from E-box elements (By similarity).	0.990

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