STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
P2RY14Purinergic receptor P2Y14. (340 aa)    
Predicted Functional Partners:
TMEM119
Transmembrane protein 119.
      
 0.621
ADORA3
Adenosine receptor A3; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family.
   
  
 0.598
MARCKSL1
MARCKS like 1.
      
 0.579
CAMK1
Calcium/calmodulin dependent protein kinase I; Belongs to the protein kinase superfamily.
      
 0.578
TREM2
Triggering receptor expressed on myeloid cells 2.
   
  
 0.565
CSF1R
Macrophage colony-stimulating factor 1 receptor; Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines in response to IL34 and CSF1, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulat [...]
   
  
 0.509
PLAUR
Plasminogen activator, urokinase receptor.
      
 0.504
P2RY13
Purinergic receptor P2Y13; Belongs to the G-protein coupled receptor 1 family.
   
 
0.452
WWOX
WW domain containing oxidoreductase.
      
 0.442
CHRNA6
Cholinergic receptor nicotinic alpha 6 subunit.
      
 0.424
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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