SPAM1 protein (Felis catus) - STRING interaction network

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Predicted Interactions

gene neighborhood

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textmining

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protein homology

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Score

SPAM1

Hyaluronidase. (508 aa)

Predicted Functional Partners:

GUSB

0.930

ARSB

0.925

IDUA

0.914

ITSN2

0.824

CD44

0.760

ITSN1

0.729

ALB

0.705

ADAM2

0.704

ZAN

0.675

GAK

0.654

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADAM2	SPAM1	ENSFCAP00000053487	ENSFCAP00000009658	ADAM metallopeptidase domain 2.	Hyaluronidase.	0.704
ADAM2	ZAN	ENSFCAP00000053487	ENSFCAP00000006360	ADAM metallopeptidase domain 2.	Zonadhesin.	0.455
ALB	CD44	ENSFCAP00000028536	ENSFCAP00000048474	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	CD44 molecule (Indian blood group).	0.742
ALB	GUSB	ENSFCAP00000028536	ENSFCAP00000006431	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family.	0.538
ALB	SPAM1	ENSFCAP00000028536	ENSFCAP00000009658	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	Hyaluronidase.	0.705
ARSB	GUSB	ENSFCAP00000054046	ENSFCAP00000006431	Arylsulfatase B; Removes sulfate groups from chondroitin-4-sulfate (C4S) and regulates its degradation (By similarity). Involved in the regulation of cell adhesion, cell migration and invasion in colonic epithelium (By similarity). In the central nervous system, is a regulator of neurite outgrowth and neuronal plasticity, acting through the control of sulfate glycosaminoglycans and neurocan levels (By similarity). Belongs to the sulfatase family.	Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family.	0.755
ARSB	IDUA	ENSFCAP00000054046	ENSFCAP00000004367	Arylsulfatase B; Removes sulfate groups from chondroitin-4-sulfate (C4S) and regulates its degradation (By similarity). Involved in the regulation of cell adhesion, cell migration and invasion in colonic epithelium (By similarity). In the central nervous system, is a regulator of neurite outgrowth and neuronal plasticity, acting through the control of sulfate glycosaminoglycans and neurocan levels (By similarity). Belongs to the sulfatase family.	Iduronidase alpha-L-.	0.966
ARSB	SPAM1	ENSFCAP00000054046	ENSFCAP00000009658	Arylsulfatase B; Removes sulfate groups from chondroitin-4-sulfate (C4S) and regulates its degradation (By similarity). Involved in the regulation of cell adhesion, cell migration and invasion in colonic epithelium (By similarity). In the central nervous system, is a regulator of neurite outgrowth and neuronal plasticity, acting through the control of sulfate glycosaminoglycans and neurocan levels (By similarity). Belongs to the sulfatase family.	Hyaluronidase.	0.925
CD44	ALB	ENSFCAP00000048474	ENSFCAP00000028536	CD44 molecule (Indian blood group).	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	0.742
CD44	SPAM1	ENSFCAP00000048474	ENSFCAP00000009658	CD44 molecule (Indian blood group).	Hyaluronidase.	0.760
GAK	ITSN1	ENSFCAP00000007628	ENSFCAP00000026342	Cyclin G associated kinase.	Intersectin 1.	0.616
GAK	ITSN2	ENSFCAP00000007628	ENSFCAP00000003974	Cyclin G associated kinase.	Intersectin 2.	0.774
GAK	SPAM1	ENSFCAP00000007628	ENSFCAP00000009658	Cyclin G associated kinase.	Hyaluronidase.	0.654
GUSB	ALB	ENSFCAP00000006431	ENSFCAP00000028536	Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family.	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	0.538
GUSB	ARSB	ENSFCAP00000006431	ENSFCAP00000054046	Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family.	Arylsulfatase B; Removes sulfate groups from chondroitin-4-sulfate (C4S) and regulates its degradation (By similarity). Involved in the regulation of cell adhesion, cell migration and invasion in colonic epithelium (By similarity). In the central nervous system, is a regulator of neurite outgrowth and neuronal plasticity, acting through the control of sulfate glycosaminoglycans and neurocan levels (By similarity). Belongs to the sulfatase family.	0.755
GUSB	IDUA	ENSFCAP00000006431	ENSFCAP00000004367	Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family.	Iduronidase alpha-L-.	0.779
GUSB	SPAM1	ENSFCAP00000006431	ENSFCAP00000009658	Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family.	Hyaluronidase.	0.930
IDUA	ARSB	ENSFCAP00000004367	ENSFCAP00000054046	Iduronidase alpha-L-.	Arylsulfatase B; Removes sulfate groups from chondroitin-4-sulfate (C4S) and regulates its degradation (By similarity). Involved in the regulation of cell adhesion, cell migration and invasion in colonic epithelium (By similarity). In the central nervous system, is a regulator of neurite outgrowth and neuronal plasticity, acting through the control of sulfate glycosaminoglycans and neurocan levels (By similarity). Belongs to the sulfatase family.	0.966
IDUA	GUSB	ENSFCAP00000004367	ENSFCAP00000006431	Iduronidase alpha-L-.	Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family.	0.779
IDUA	SPAM1	ENSFCAP00000004367	ENSFCAP00000009658	Iduronidase alpha-L-.	Hyaluronidase.	0.914