STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SAPCD2Suppressor APC domain containing 2. (407 aa)    
Predicted Functional Partners:
LRRN4CL
LRRN4 C-terminal like.
      
 0.656
PDCL2
Phosducin like 2.
      
 0.647
TMEM45B
Transmembrane protein 45B.
      
 0.628
IGSF9B
Immunoglobulin superfamily member 9B.
      
 0.625
TMPRSS11A
Transmembrane protease serine; Belongs to the peptidase S1 family.
      
 0.613
STARD13
StAR related lipid transfer domain containing 13.
      
 0.549
TLCD4
TLCD4-RWDD3 readthrough.
      
 0.548
CACNG4
Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
      
 0.542
PREX2
Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2.
      
 0.539
NGEF
Neuronal guanine nucleotide exchange factor.
      
 0.533
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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