STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLEKHG2Pleckstrin homology and RhoGEF domain containing G2. (1409 aa)    
Predicted Functional Partners:
PIK3R3
Uncharacterized protein.
    
 0.622
ENSFCAP00000051257
Uncharacterized protein.
      
 0.620
LGI4
Leucine rich repeat LGI family member 4.
      
 0.592
SUPT5H
Transcription elongation factor SPT5.
    
 0.475
PLCE1
Phosphoinositide phospholipase C.
      
 0.455
ZNF646
Zinc finger protein 646.
  
 
  0.437
PPP1R3F
Protein phosphatase 1 regulatory subunit 3F.
  
 
   0.429
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.