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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MEPCEMethylphosphate capping enzyme. (689 aa)    
Predicted Functional Partners:
LARP7
La ribonucleoprotein domain family member 7.
    
 0.998
HEXIM1
HEXIM P-TEFb complex subunit 1.
    
 0.990
HEXIM2
HEXIM P-TEFb complex subunit 2.
    
 
 0.952
CDK9
Cyclin dependent kinase 9; Belongs to the protein kinase superfamily.
    
 
 0.916
NELFE
Negative elongation factor complex member E.
    
 
 0.833
CCNT1
CYCLIN domain-containing protein; Belongs to the cyclin family.
    
 
 0.810
TBC1D2B
TBC1 domain family member 2B.
      
 0.803
MYO1G
Myosin IG; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
      
 0.699
SART3
Spliceosome associated factor 3, U4/U6 recycling protein.
    
 
 0.688
METTL16
U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; RNA N6-methyltransferase that methylates adenosine residues of a subset of RNAs and plays a key role in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6- methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure. In presence of S-adenosyl-L-methionine, binds the 3'-UTR region of MAT2A mRNA and specifical [...]
    
 
 0.684
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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