Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
PLXDC2Plexin domain containing 2. (529 aa)    
Predicted Functional Partners:
SLC22A3
Solute carrier family 22 member 3.
      
 0.564
KLHL25
Kelch like family member 25.
      
 0.562
EYA4
Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.
      
 0.492
TUBGCP3
Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family.
      
 0.486
TRAPPC8
Trafficking protein particle complex 8.
      
 0.485
ATP11A
Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
      
 0.475
CGRRF1
Cell growth regulator with ring finger domain 1.
      
 0.466
BAIAP2L1
BAI1 associated protein 2 like 1.
      
 0.448
RNF38
Ring finger protein 38.
   
  
 0.433
RNF44
Ring finger protein 44.
   
  
 0.433
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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