Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
DIRAS2DIRAS family GTPase 2. (199 aa)    
Predicted Functional Partners:
LRRC17
Leucine rich repeat containing 17.
    
 0.851
PIK3CB
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family.
    
 0.842
RARRES2
Retinoic acid receptor responder 2.
      
 0.838
VENTX
VENT homeobox.
     
 0.800
CREB3L1
cAMP responsive element binding protein 3 like 1.
      
 0.735
RAPGEF4
Rap guanine nucleotide exchange factor 4.
   
 0.731
RAP1GDS1
Rap1 GTPase-GDP dissociation stimulator 1.
    
 0.661
AKR1D1
Aldo-keto reductase family 1 member D1.
    
 
 0.658
AKR1C3
Aldo_ket_red domain-containing protein.
    
 
 0.658
RNF19B
RBR-type E3 ubiquitin transferase.
    
  0.609
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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