STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIRAS2DIRAS family GTPase 2. (199 aa)    
Predicted Functional Partners:
PIK3CB
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family.
    
 0.851
ITSN2
Intersectin 2.
   
 0.826
SCIMP
SLP adaptor and CSK interacting membrane protein.
   
    0.789
ITSN1
Intersectin 1.
    
 0.729
LAMTOR2
Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2.
    
 0.695
SGCE
Sarcoglycan epsilon.
      
 0.663
RAPGEF4
Rap guanine nucleotide exchange factor 4.
    
 0.663
RASGRF2
Ras protein specific guanine nucleotide releasing factor 2.
   
 0.631
RASGRF1
Ras protein specific guanine nucleotide releasing factor 1.
   
 0.631
NAP1L5
Nucleosome assembly protein 1 like 5; Belongs to the nucleosome assembly protein (NAP) family.
   
 
 0.629
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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