Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MMP12Matrix metallopeptidase 12. (470 aa)    
Predicted Functional Partners:
MMP9
Matrix metallopeptidase 9.
   
 0.854
NFKB1
Nuclear factor kappa B subunit 1.
   
 0.809
RELA
RELA proto-oncogene, NF-kB subunit.
    
 0.806
MMP1
Matrix metallopeptidase 1.
   
 0.748
LOC101083957
ZnMc domain-containing protein.
   
 0.748
TIMP3
TIMP metallopeptidase inhibitor 3.
   
 0.728
TIMP2
TIMP metallopeptidase inhibitor 2.
   
 0.722
DCN
Decorin; May affect the rate of fibrils formation.
   
 0.705
MMP13
Matrix metallopeptidase 13.
   
 0.693
TIMP1
TIMP metallopeptidase inhibitor 1.
   
 0.653
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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