FAM126A protein (Felis catus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

FAM126A

Family with sequence similarity 126 member A. (521 aa)

Predicted Functional Partners:

TTC7A

0.948

TTC7B

0.945

PHKA1

0.816

PI4KA

0.805

PHKA2

0.734

SHPK

0.725

PPP3CB

0.710

RCAN3

0.710

IL1RAPL2

0.665

GJC2

0.647

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FAM126A	GJC2	ENSFCAP00000010232	ENSFCAP00000006614	Family with sequence similarity 126 member A.	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	0.647
FAM126A	IL1RAPL2	ENSFCAP00000010232	ENSFCAP00000046739	Family with sequence similarity 126 member A.	Interleukin 1 receptor accessory protein like 2.	0.665
FAM126A	PHKA1	ENSFCAP00000010232	ENSFCAP00000006605	Family with sequence similarity 126 member A.	Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I.	0.816
FAM126A	PHKA2	ENSFCAP00000010232	ENSFCAP00000034429	Family with sequence similarity 126 member A.	Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I.	0.734
FAM126A	PI4KA	ENSFCAP00000010232	ENSFCAP00000055682	Family with sequence similarity 126 member A.	Phosphatidylinositol 4-kinase alpha; Belongs to the PI3/PI4-kinase family.	0.805
FAM126A	PPP3CB	ENSFCAP00000010232	ENSFCAP00000025161	Family with sequence similarity 126 member A.	Serine/threonine-protein phosphatase.	0.710
FAM126A	RCAN3	ENSFCAP00000010232	ENSFCAP00000052859	Family with sequence similarity 126 member A.	RCAN family member 3.	0.710
FAM126A	SHPK	ENSFCAP00000010232	ENSFCAP00000007338	Family with sequence similarity 126 member A.	FGGY_N domain-containing protein.	0.725
FAM126A	TTC7A	ENSFCAP00000010232	ENSFCAP00000050343	Family with sequence similarity 126 member A.	Tetratricopeptide repeat domain 7A.	0.948
FAM126A	TTC7B	ENSFCAP00000010232	ENSFCAP00000055959	Family with sequence similarity 126 member A.	Tetratricopeptide repeat domain 7B.	0.945
GJC2	FAM126A	ENSFCAP00000006614	ENSFCAP00000010232	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	Family with sequence similarity 126 member A.	0.647
IL1RAPL2	FAM126A	ENSFCAP00000046739	ENSFCAP00000010232	Interleukin 1 receptor accessory protein like 2.	Family with sequence similarity 126 member A.	0.665
PHKA1	FAM126A	ENSFCAP00000006605	ENSFCAP00000010232	Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I.	Family with sequence similarity 126 member A.	0.816
PHKA1	PHKA2	ENSFCAP00000006605	ENSFCAP00000034429	Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I.	Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I.	0.957
PHKA1	PI4KA	ENSFCAP00000006605	ENSFCAP00000055682	Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I.	Phosphatidylinositol 4-kinase alpha; Belongs to the PI3/PI4-kinase family.	0.451
PHKA1	PPP3CB	ENSFCAP00000006605	ENSFCAP00000025161	Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I.	Serine/threonine-protein phosphatase.	0.737
PHKA1	RCAN3	ENSFCAP00000006605	ENSFCAP00000052859	Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I.	RCAN family member 3.	0.710
PHKA1	TTC7A	ENSFCAP00000006605	ENSFCAP00000050343	Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I.	Tetratricopeptide repeat domain 7A.	0.709
PHKA1	TTC7B	ENSFCAP00000006605	ENSFCAP00000055959	Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I.	Tetratricopeptide repeat domain 7B.	0.826
PHKA2	FAM126A	ENSFCAP00000034429	ENSFCAP00000010232	Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I.	Family with sequence similarity 126 member A.	0.734