Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
INPP5BInositol polyphosphate-5-phosphatase B. (913 aa)    
Predicted Functional Partners:
SACM1L
SAC1 like phosphatidylinositide phosphatase.
 
  
 0.991
OCRL
OCRL inositol polyphosphate-5-phosphatase.
    
  0.981
INPP4A
Inositol polyphosphate-4-phosphatase type I A.
    
 0.930
INPP4B
Inositol polyphosphate-4-phosphatase type II B.
    
 0.924
PTEN
Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.
     
 0.911
PIK3C2B
Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta; Belongs to the PI3/PI4-kinase family.
   
 
 0.910
PIK3C2G
Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma; Belongs to the PI3/PI4-kinase family.
   
 
 0.910
PIK3C2A
Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha; Belongs to the PI3/PI4-kinase family.
   
 
 0.910
INPP5E
Inositol polyphosphate-5-phosphatase E.
     
 0.909
PIP5K1A
Phosphatidylinositol-4-phosphate 5-kinase type 1 alpha.
     
 0.908
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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