Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
MPP5Membrane palmitoylated protein 5; Belongs to the MAGUK family. (675 aa)    
Predicted Functional Partners:
PATJ
PATJ crumbs cell polarity complex component.
   
 0.998
AMOT
Angiomotin.
    
 0.996
MPDZ
Multiple PDZ domain crumbs cell polarity complex component.
   
 0.990
LIN7A
Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family.
    
 0.977
CRB3
Crumbs cell polarity complex component 3.
    
 0.972
AMOTL1
Angiomotin like 1.
    
 0.968
PARD6A
Par-6 family cell polarity regulator alpha.
   
 0.948
CRB1
Crumbs cell polarity complex component 1.
    
 0.934
MPP4
Membrane palmitoylated protein 4; Belongs to the MAGUK family.
    
  0.904
UBE3A
Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates.
    
  0.894
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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