Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DBHDopamine beta-hydroxylase. (610 aa)    
Predicted Functional Partners:
PNMT
Phenylethanolamine N-methyltransferase.
   
 
 0.985
COMT
Catechol-O-methyltransferase.
     
 0.958
MAOA
Amine oxidase.
   
 
 0.949
DDC
Dopa decarboxylase.
     
 0.949
TOMT
Uncharacterized protein.
     
 0.947
MAOB
Amine oxidase.
   
 
 0.946
TH
Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
   
  
 0.915
AOC2
Amine oxidase.
     
 0.896
PHOX2B
Paired like homeobox 2B.
   
 
 0.835
PAH
Phenylalanine hydroxylase.
   
  
 0.797
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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