Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PFN1Profilin; Belongs to the profilin family. (140 aa)    
Predicted Functional Partners:
VASP
Vasodilator stimulated phosphoprotein; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family.
   
 0.734
CFL1
ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.
   
 0.715
CFL2
Cofilin 2; Belongs to the actin-binding proteins ADF family.
   
 0.704
ACTB
Actin beta.
   
 0.641
APBB1IP
Amyloid beta precursor protein binding family B member 1 interacting protein.
    
 0.625
DIAPH2
Diaphanous related formin 2.
    
 0.625
DIAPH1
Diaphanous related formin 1.
    
 0.625
EVL
Enah/Vasp-like.
   
 0.610
ENSFCAP00000047404
Uncharacterized protein.
   
 0.603
MYD88
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
   
 
 0.584
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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