Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ANKZF1Ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1. (761 aa)    
Predicted Functional Partners:
NEMF
Nuclear export mediator factor.
   
 0.922
VCP
Valosin containing protein; Belongs to the AAA ATPase family.
   
 0.767
SPATA5
Spermatogenesis associated 5.
   
 0.711
SPATA5L1
Spermatogenesis associated 5 like 1.
   
 0.711
LTN1
Listerin E3 ubiquitin protein ligase 1.
    
 0.694
ERMN
Ermin.
   
 0.668
ENSFCAP00000053845
Uncharacterized protein.
      
 0.647
EIF6
Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...]
    
 
 0.616
ELAC1
ElaC ribonuclease Z 1.
   
  
 0.604
UBE4A
Ubiquitination factor E4A.
    
 
 0.589
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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