STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa)    
Predicted Functional Partners:
TAB1
TGF-beta activated kinase 1 (MAP3K7) binding protein 1.
    
 0.999
MAP3K7
Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
   
 0.999
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.999
IRAK1
Interleukin 1 receptor associated kinase 1.
    
 0.998
RIPK1
Receptor interacting serine/threonine kinase 1.
    
 0.998
IKBKG
Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.
    
 0.998
TAB3
TGF-beta activated kinase 1 (MAP3K7) binding protein 3.
  
0.998
RIPK2
Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains.
    
 0.982
CHUK
Component of inhibitor of nuclear factor kappa B kinase complex.
    
 0.982
TRAF2
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.980
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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