Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
IVNS1ABPInfluenza virus NS1A binding protein. (642 aa)    
Predicted Functional Partners:
PRPSAP1
Phosphoribosyl pyrophosphate synthetase associated protein 1.
    
 
 0.943
PRPSAP2
Phosphoribosyl pyrophosphate synthetase associated protein 2.
    
 
 0.854
TRMT1L
tRNA methyltransferase 1 like; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
   
  
 0.846
SWT1
SWT1 RNA endoribonuclease homolog.
      
 0.846
RGS7
Regulator of G protein signaling 7.
      
 0.731
OPN3
Opsin 3; Belongs to the G-protein coupled receptor 1 family.
     
 0.712
RNF2
Ring finger protein 2.
      
 0.710
CUL3
Cullin 3; Belongs to the cullin family.
    
 0.709
DAND5
DAN domain BMP antagonist family member 5.
      
 0.628
LOC102901749
Uncharacterized protein.
    
 
 0.578
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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