| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AHSG | ALB | ENSFCAP00000058422 | ENSFCAP00000028536 | Alpha 2-HS glycoprotein. | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | 0.949 |
| AHSG | GC | ENSFCAP00000058422 | ENSFCAP00000004482 | Alpha 2-HS glycoprotein. | GC vitamin D binding protein. | 0.879 |
| AHSG | LOC101095098 | ENSFCAP00000058422 | ENSFCAP00000038697 | Alpha 2-HS glycoprotein. | Uncharacterized protein. | 0.684 |
| AHSG | LOC101096750 | ENSFCAP00000058422 | ENSFCAP00000024018 | Alpha 2-HS glycoprotein. | Uricase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin. Belongs to the uricase family. | 0.437 |
| AHSG | RBP4 | ENSFCAP00000058422 | ENSFCAP00000045741 | Alpha 2-HS glycoprotein. | Retinol binding protein 4; Retinol-binding protein that mediates retinol transport in blood plasma. Delivers retinol from the liver stores to the peripheral tissues. Transfers the bound all-trans retinol to STRA6, that then facilitates retinol transport across the cell membrane. | 0.565 |
| AHSG | TTR | ENSFCAP00000058422 | ENSFCAP00000010512 | Alpha 2-HS glycoprotein. | Transthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. | 0.716 |
| ALB | AHSG | ENSFCAP00000028536 | ENSFCAP00000058422 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Alpha 2-HS glycoprotein. | 0.949 |
| ALB | APP | ENSFCAP00000028536 | ENSFCAP00000001445 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Amyloid-beta A4 protein; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those mediated by G(O) an [...] | 0.709 |
| ALB | GC | ENSFCAP00000028536 | ENSFCAP00000004482 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | GC vitamin D binding protein. | 0.630 |
| ALB | LOC101096750 | ENSFCAP00000028536 | ENSFCAP00000024018 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Uricase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin. Belongs to the uricase family. | 0.548 |
| ALB | RBP4 | ENSFCAP00000028536 | ENSFCAP00000045741 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Retinol binding protein 4; Retinol-binding protein that mediates retinol transport in blood plasma. Delivers retinol from the liver stores to the peripheral tissues. Transfers the bound all-trans retinol to STRA6, that then facilitates retinol transport across the cell membrane. | 0.720 |
| ALB | TTR | ENSFCAP00000028536 | ENSFCAP00000010512 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Transthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. | 0.767 |
| APP | ALB | ENSFCAP00000001445 | ENSFCAP00000028536 | Amyloid-beta A4 protein; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those mediated by G(O) an [...] | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | 0.709 |
| APP | TTR | ENSFCAP00000001445 | ENSFCAP00000010512 | Amyloid-beta A4 protein; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those mediated by G(O) an [...] | Transthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. | 0.694 |
| ATP8 | TTR | ENSFCAP00000025713 | ENSFCAP00000010512 | ATP synthase protein 8; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subuni [...] | Transthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. | 0.678 |
| GC | AHSG | ENSFCAP00000004482 | ENSFCAP00000058422 | GC vitamin D binding protein. | Alpha 2-HS glycoprotein. | 0.879 |
| GC | ALB | ENSFCAP00000004482 | ENSFCAP00000028536 | GC vitamin D binding protein. | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | 0.630 |
| GC | LOC101095098 | ENSFCAP00000004482 | ENSFCAP00000038697 | GC vitamin D binding protein. | Uncharacterized protein. | 0.595 |
| GC | RBP4 | ENSFCAP00000004482 | ENSFCAP00000045741 | GC vitamin D binding protein. | Retinol binding protein 4; Retinol-binding protein that mediates retinol transport in blood plasma. Delivers retinol from the liver stores to the peripheral tissues. Transfers the bound all-trans retinol to STRA6, that then facilitates retinol transport across the cell membrane. | 0.810 |
| GC | TTR | ENSFCAP00000004482 | ENSFCAP00000010512 | GC vitamin D binding protein. | Transthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. | 0.830 |