STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
WDR1WD repeat domain 1. (606 aa)    
Predicted Functional Partners:
CAPZB
F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
   
 
 0.833
ACTR3
Actin related protein 3; Belongs to the actin family.
   
 0.805
ACTR3B
Uncharacterized protein; Belongs to the actin family.
   
 0.805
CFL1
ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.
   
 
 0.800
ENSFCAP00000047404
Uncharacterized protein.
   
 
 0.800
ZNF518B
Zinc finger protein 518B.
      
 0.723
CFL2
Cofilin 2; Belongs to the actin-binding proteins ADF family.
   
 
 0.702
ACAD8
Acyl-CoA dehydrogenase family member 8.
      
 0.678
LOC102901344
Uncharacterized protein.
      
 0.662
VCL
Vinculin.
   
 
 0.638
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
Server load: low (24%) [HD]