Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
RLNRelaxin A chain; Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals; Belongs to the insulin family. (180 aa)    
Predicted Functional Partners:
RXFP1
Relaxin family peptide receptor 1.
    
 0.992
RXFP2
Relaxin family peptide receptor 2.
    
 0.987
RXFP3
Relaxin family peptide receptor 3.
     
 0.969
RLN3
Relaxin 3.
     
 0.966
INSL3
IlGF domain-containing protein.
     
 0.957
LGR4
Leucine rich repeat containing G protein-coupled receptor 4.
    
 0.740
INSL6
Insulin-like peptide INSL6; May have a role in sperm development and fertilization. Belongs to the insulin family.
      
 0.732
LGR5
Leucine rich repeat containing G protein-coupled receptor 5.
    
  0.663
LGR6
LRRNT domain-containing protein.
    
 0.545
TSHR
Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism.
    
 0.504
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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