STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
REG4Regenerating family member 4. (158 aa)    
Predicted Functional Partners:
TFF2
Trefoil factor 2.
   
  
 0.698
NOTCH2
Notch receptor 2.
   
 0.597
ABLIM2
Actin binding LIM protein family member 2.
      
 0.567
TFF3
Trefoil factor 3; Involved in the maintenance and repair of the intestinal mucosa. Promotes the mobility of epithelial cells in healing processes (motogen) (By similarity).
   
  
 0.536
LGR5
Leucine rich repeat containing G protein-coupled receptor 5.
    
 0.535
GUCA2A
Guanylate cyclase activator 2A.
   
  
 0.523
SPINK4
Serine peptidase inhibitor, Kazal type 4.
   
  
 0.518
CHGB
Chromogranin B.
    
 0.490
OLFM4
Olfactomedin 4.
      
 0.483
ATOH1
Atonal bHLH transcription factor 1.
   
  
 0.480
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.