Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PAPPAPappalysin 1. (1629 aa)    
Predicted Functional Partners:
IGFBP5
Insulin like growth factor binding protein 5.
    
 0.846
STC2
Stanniocalcin 2.
    
 
 0.817
PRG3
Proteoglycan 3, pro eosinophil major basic protein 2.
    
 0.774
ENSFCAP00000053888
Uncharacterized protein.
    
 0.774
IGFBP4
Insulin like growth factor binding protein 4.
   
 
 0.756
IFNGR2
Interferon gamma receptor 2.
      
 0.746
ANP32E
Acidic nuclear phosphoprotein 32 family member E.
    
   0.690
ANP32A
LRRcap domain-containing protein.
    
   0.690
IGF1
Insulin like growth factor 1.
    
 0.652
APMAP
Adipocyte plasma membrane associated protein.
      
 0.589
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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