Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
CLEC16AC-type lectin domain containing 16A. (1045 aa)    
Predicted Functional Partners:
GPN1
GPN-loop GTPase; Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.
 
  
   0.853
RNF41
Ring finger protein 41.
    
 
 0.773
VPS26B
VPS26, retromer complex component B.
    
 
 0.717
TBC1D12
TBC1 domain family member 12.
      
 0.655
DEXI
Dexi homolog.
      
 0.618
D2HGDH
D-2-hydroxyglutarate dehydrogenase.
      
 0.572
TFB1M
rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
 
  
   0.570
CLECL1
C-type lectin domain-containing protein.
    
 
 0.557
USP8
Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family.
      
 0.554
WDR44
WD repeat domain 44.
      
 0.540
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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