STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PGLYRP4Peptidoglycan recognition protein 4. (371 aa)    
Predicted Functional Partners:
KRT24
Keratin 24; Belongs to the intermediate filament family.
      
 0.577
KLK12
Kallikrein related peptidase 12; Belongs to the peptidase S1 family.
      
 0.577
KRT78
Keratin 78; Belongs to the intermediate filament family.
   
  
 0.466
KLK13
Kallikrein related peptidase 13; Belongs to the peptidase S1 family.
      
 0.450
TGM1
Transglutaminase 1.
      
 0.416
INHBA
Inhibin beta A chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins (By similarity).
      
 0.416
MAFF
MAF bZIP transcription factor F.
      
 0.416
GAS6
Growth arrest specific 6.
      
 0.414
FOSL1
FOS like 1, AP-1 transcription factor subunit.
      
 0.407
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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