Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TMED8Transmembrane p24 trafficking protein family member 8. (315 aa)    
Predicted Functional Partners:
ALDH18A1
Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
  
 
 0.793
TRAPPC5
Trafficking protein particle complex subunit 5; May play a role in vesicular transport from endoplasmic reticulum to Golgi.
   
  
 0.643
SLC50A1
Sugar transporter SWEET; Mediates sugar transport across membranes.
      
 0.611
AFAP1L2
Actin filament associated protein 1 like 2.
      
 0.608
MYH14
Myosin heavy chain 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
      
 0.602
STX8
Syntaxin 8.
    
   0.578
CAMSAP3
Calmodulin regulated spectrin associated protein family member 3.
      
 0.568
L3HYPDH
Trans-L-3-hydroxyproline dehydratase.
    
 0.559
CASK
Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family.
  
  
 0.554
TMED10
Transmembrane p24 trafficking protein 10.
   
  
 0.536
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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