STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HSPA5Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family. (654 aa)    
Predicted Functional Partners:
ATF6
Activating transcription factor 6.
    
 0.999
HSP90B1
Heat shock protein 90 beta family member 1.
   
 0.999
HYOU1
Hypoxia up-regulated 1.
  
0.994
ERN1
Endoplasmic reticulum to nucleus signaling 1.
    
 0.993
EIF2AK3
Eukaryotic translation initiation factor 2 alpha kinase 3.
   
 0.992
DNAJB11
J domain-containing protein.
  
 0.984
MANF
Mesencephalic astrocyte derived neurotrophic factor.
   
 
 0.982
PDIA3
Protein disulfide-isomerase.
   
 0.978
DNAJC10
DnaJ heat shock protein family (Hsp40) member C10.
  
 0.969
CALR
Calreticulin.
   
 0.967
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.